Organo-Metalloid Compounds
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Filtered Search Results
Medchemexpress LLC 2,5,8,11,14-pentaoxahexadecan-16-ol, 1-phenyl | 57671-28-0 | MFCD06797154 | 98.6% | 328.40 g/mol | C17H28O6 | 5 G
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BnO-PEG5-OH is a benzyl-protected PEG5 primary alcohol used as a short spacer or linker building block in PROTAC and conjugation chemistries. It provides a PEG chain with a terminal hydroxyl group masked by a benzyl protecting group, allowing selective deprotection and downstream functionalization.
- Provides a short polyethylene glycol spacer for linker design
- Contains a benzyl-protected terminal hydroxyl for selective deprotection
- Suitable for building block use in PROTAC and bioconjugate synthesis
- Available in multiple pack sizes for small-scale synthesis
- Offers high reported purity for synthetic applications
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Medchemexpress LLC Azide-PEG3-tos | 178685-33-1 | 329.37 g/mol | C13H19N3O5S | 250 MG
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Azide-PEG3-Tos is a heterobifunctional PEG linker containing an azide functional group for click chemistry. It acts as a non-cleavable, three-unit PEG linker used in the synthesis of PROTACs and antibody-drug conjugates, and participates in copper-catalyzed and strain-promoted azide-alkyne cycloaddition reactions.
- Heterobifunctional PEG linker with azide group.
- Molecular weight 329.37 g/mol.
- Chemical formula C13H19N3O5S.
- CAS number 178685-33-1.
- Available in 250 MG packaging; other sizes available.
- Storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Applications: PROTAC synthesis, ADC construction, click chemistry.
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Medchemexpress LLC Bis-PEG5-PFP ester | 1334177-78-4 | 100 MG
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Bis-PEG5-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
- Contains two different ligands connected by a linker.
- One ligand targets an E3 ubiquitin ligase; the other targets the protein.
- Exploits the intracellular ubiquitin-proteasome system.
- Selectively degrades target proteins.
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Medchemexpress LLC N- Amino-PEG5 -N-bis | 25MG
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N- Amino-PEG5 -N-bis | 25MG
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Medchemexpress LLC Azido-PEG3-C-Boc | 500MG
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Azido-PEG3-C-Boc | 500MG
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Medchemexpress LLC Nh-bis(peg3-boc) | 1814901-03-5 | MFCD29912753 | 98.0% | C26H51NO10 | 25 MG
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Nh-bis(peg3-boc) | 1814901-03-5 | MFCD29912753 | 98.0% | C26H51NO10 | 25 MG
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Medchemexpress LLC Lipoamide-PEG3-Mal | 1314378-19-2 | 99.6% | C25H41N3O7S2 | 1 MG
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Lipoamide-PEG3-Mal is a PEG-based PROTAC linker designed for the synthesis of PROTACs. These molecules feature two distinct ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other binding to a specific target protein. This mechanism exploits the intracellular ubiquitin-proteasome system to facilitate the selective degradation of target proteins.
- PEG-based linker
- Used in the synthesis of PROTACs
- Contains two different ligands connected by a linker
- One ligand targets an E3 ubiquitin ligase
- Other ligand targets the target protein
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC M-PEG3-succinimidyl carbonate | 477775-77-2 | 99.4% | C12H19NO8 | 1 G
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m-PEG3-succinimidyl carbonate is a PEG-based PROTAC linker. It can be used in the synthesis of PROTACs, which contain two different ligands connected by a linker. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Useful for the synthesis of PROTACs
- Utilizes the intracellular ubiquitin-proteasome system
- Enables selective degradation of target proteins
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Medchemexpress LLC N- Azido-PEG3 -N-bis | 100MG
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N- Azido-PEG3 -N-bis | 100MG
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Medchemexpress LLC Azide-PEG3-Desthiobi 10mg
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Azide-PEG3-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1] Azide-PEG3-Desthiobiotin is a click chemistry reagent it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
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Medchemexpress LLC (S,R,S)-AHPC-C2-PEG3-BCN | 2876198-36-4 | 98.4% | 810.01 | 50 MG
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(S,R,S)-AHPC-C2-PEG3-BCN (Compound 16b) is a VHL ligand. It is used for the synthesis of PROTACs.
- Utilized for the synthesis of PROTACs
- VHL ligand
- Related to cancer targeted therapy
- Inhibitor
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Medchemexpress LLC O,O'-[Oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis[hydroxylamine] | 98627-70-4 | 98.0% | C8H20N2O5 | 100 MG
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This product, Bis-aminooxy-PEG3, is a PEG-based PROTAC linker. It has a molecular weight of 224.25 and appears as a colorless to light yellow liquid.
- Consistent with structure based on ¹H NMR spectrum
- Consistent with structure based on MS
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![Medchemexpress LLC Propanoic acid, 3-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester | 186020-66-6 | 95.0% | 278.34 g/mol | C13H26O6 | 25 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000202875.png-250.jpg)
Medchemexpress LLC Propanoic acid, 3-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester | 186020-66-6 | 95.0% | 278.34 g/mol | C13H26O6 | 25 G
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Hydroxy-PEG3-(CH2)2-Boc is a Boc-protected, hydroxy-terminated polyethylene glycol linker used as a building block in linker and PROTAC synthesis. Supplied as a white to off-white solid, it has a typical purity of 95.0% and a molecular weight of 278.34 g/mol (CAS 186020-66-6).
- Boc-protected hydroxy-terminated PEG3 linker for synthetic chemistry.
- Typical purity 95.0% by NMR.
- Molecular weight 278.34 g/mol.
- Chemical formula C13H26O6.
- Supplied as a 25 g package for laboratory research use only.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Bis-PEG5-NHS ester | 756526-03-1 | 99.8% | 532.50 g/mol | C22H32N2O13 | 25 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Bis-PEG5-NHS ester is a bifunctional PEG-based cleavable NHS-activated ester used for conjugation to primary amines in the synthesis of antibody-drug conjugates (ADCs), PROTACs, and other bioconjugates. Supplied as a solid for research use, it facilitates PEGylation and formation of cleavable linkers in medicinal chemistry and chemical biology workflows.
- Cleavable PEG5 NHS ester for selective amine conjugation.
- Suitable for ADC and PROTAC linker synthesis.
- High purity, suitable for synthetic applications.
- Molecular weight 532.50 g/mol, chemical formula C22H32N2O13.
- Available in small-scale research quantities, e.g. 25 MG.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC (E)-Cyclooct-2-en-1-yl (2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)carbamate | 98.4% | 344.45 | C17H32N2O5 | 10 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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TCO-PEG3-NH2 is a click-chemistry reagent composed of a trans-cyclooctene (TCO) group linked to a three-unit polyethylene glycol spacer terminating in a primary amine. It enables fast bioorthogonal inverse-electron-demand Diels-Alder (iEDDA) reactions with tetrazine-functionalized partners and amine-mediated conjugation for site-specific labeling of biomolecules.
- Enables rapid iEDDA bioorthogonal chemistry for fast conjugation.
- Terminal primary amine allows amide bond formation with carboxyl groups.
- Three-unit PEG spacer improves aqueous solubility and reduces steric hindrance.
- Suitable for site-specific labeling and bioconjugation workflows.
- Typically supplied as a small solid quantity for laboratory use.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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